Physical examination of vascular endothelial growth factor is mainly to check local tissue ischemia, inflammation, tumor and other conditions. 1. Local tissue ischemia: when ischemia occurs in body tissues, the body may up-regulate the expression of VEGF genes, thus inducing vascular meristem to improve the symptoms of ischemia. 2. Inflammation: Clinical studies have found that VEGF has a physiological role in promoting the aggregation of inflammatory diseases, endothelial permeability, and up-regulation of adhesion molecules, thus suggesting that elevated VEGF may be related to inflammation. 3. Tumor: Tumor growth is extremely dependent on blood supply, so the process of vascular regeneration can significantly affect the growth and metastasis of tumors, and vascular endothelial growth factor plays a more important role in the growth of newborn blood vessels, so its high expression is often associated with tumors. If the result of physical examination suggests that VEGF is highly expressed, it is recommended that the examiner should undergo further examination to clarify the cause of the disease, so as to carry out targeted treatment.