Is a biopsy used for gynecologic ASCUS?

If the cervical cytology result is ASCUS, colposcopic biopsy is recommended for HPV-positive patients, while HPV-negative patients should be followed up without biopsy for the time being. Cervical cytology is currently performed using a liquid-based thin-layer cell kit to collect exfoliated cells from the cervix for examination, i.e., TCT, and a TCT result of ASCUS indicates that the nature of the atypical squamous cells is undetermined, and that they are either benign, with active cellular proliferation, or potentially malignant, and cannot be definitively classified as such. In the case of ASCUS, the presence of squamous intraepithelial neoplasia is more likely if HPV (human papillomavirus) is positive, and there is a greater likelihood of development of cervical cancer, so the negative or positive HPV is used as the basis for whether or not to perform a biopsy. For ASCUS patients, if the HPV test is positive, colposcopic biopsy is recommended to further clarify the presence of intraepithelial neoplasia; if the HPV test is negative, follow-up observation can be carried out for six months to one year, and biopsy is recommended if the follow-up test is still ASCUS. It is recommended that patients consult a specialist, analyze the results of TCT and other tests, and follow the doctor’s instructions for further examination and treatment.