Prednisone tablets usually refers to prednisone acetate tablets, eat the drug fat will usually lose weight back, normal people eat prednisone acetate tablets for a long time or in large quantities, will appear centripetal obesity, which is a common adverse effect of taking adrenal glucocorticoids. Generally after stopping the drug by adjusting the diet, with exercise and other ways, obesity will gradually recover, only this process may take a longer time. Prednisone acetate is an adrenal glucocorticoid that affects the kidneys and causes water and sodium retention. It can also increase appetite, leading to excessive intake of nutrients and causing edema and centripetal obesity. However, the appetite will gradually return to normal after stopping the drug, and the water and sodium retention will gradually disappear with metabolism, and the obesity will be relieved. However, in order to slim back down, a combination of diet control and proper exercise is needed for a comprehensive regimen. Therefore, after stopping taking prednisone acetate tablets, you should try to control your diet, especially to reduce the intake of high-fat and high-calorie foods, such as fatty meat, fried chicken, hot pot, barbecue, cakes, etc. To ensure adequate supply of nutrition, eat more fresh fruits and vegetables as appropriate. In the case of physical state allows, properly increase the amount of exercise, such as walking, jogging, etc., can consume calories, reduce the excess body fat, you will gradually lose back.