Symptoms that can be experienced with elevated lipase are upper abdominal pain, jaundice, pain in the liver area, nausea and vomiting. Mild elevations can also occur without symptoms. Lipase is a water-soluble enzyme that catalyzes the hydrolysis of ester bonds in lipids and is the main substance that degrades fats in the human digestive system. Elevated lipase can be seen in pancreatic diseases, liver and gallbladder diseases. 1. Pancreatitis: the most common symptom of acute pancreatitis is severe burning pain in the upper abdomen radiating to the back, and elevated lipase can occur; chronic pancreatitis can lead to diabetes, and elevated lipase can also occur during an acute attack. In pancreatic cancer, lipase may be mildly elevated and may be accompanied by jaundice. 2. Liver and gallbladder diseases: Liver and gallbladder diseases, such as cholecystitis, can also show elevated lipase, with common symptoms such as right upper abdominal pain, nausea, vomiting, and occasionally fever. If lipase is higher than the normal range value, we should consult doctor in time, find out the cause of the disease and treat it without authorization, pay attention to low-fat and low-protein diet, and have regular checkups.