Eye socket pain connected with headache nausea may be glaucoma, cluster headache, brain tumor and other diseases. 1. Glaucoma: It is an increase in intraocular pressure due to an abnormality in one of the links in the atrial fluid circulation, which leads to headaches. It may also be genetically caused by optic nerve atrophy and visual field defects, with symptoms such as eye swelling, eye pain, blepharospasm, and nausea, which may also lead to headaches. 2. Cluster headache: It is a headache induced by genetic factors or vasodilatation, and the pain is usually fixed in one side of the eye socket, which can be radiated to the whole head, and nausea can also occur. 3. Brain tumor: it is due to a variety of factors together resulting in the formation of local hyperplasia and abnormal differentiation of the new tissue, the patient can show headache, vomiting, vision loss, limb movement disorders and other symptoms. Eye socket pain with headache and nausea may also be seen in migraine, cerebral hemorrhage and other causes, if the symptoms of eye socket pain with headache and nausea, persistent and unrelieved, you need to seek medical treatment.