The cost of self-funded liver transplantation ranges from 250,000 to 700,000 yuan, depending on the region of consultation, the source of donor liver, the severity of the disease, and the post-operative situation. 1. Consultation area: Generally speaking, developed areas such as economically developed areas, coastal cities, first-tier cities, provincial capitals and other developed areas have higher consumption level, so the operation cost is also higher accordingly. 2. Liver source: If the liver is donated by relatives, the cost is about 250,000 dollars without the cost of liver source; if the liver source is donated by the donor after brain death, the cost is about 550,000 dollars. 3. The severity of the disease: if the disease is more serious, the operation will be more difficult and complicated, and the treatment cost will be higher accordingly. 4. Post-operation situation: post-operation may involve patients taking anti-rejection drugs, and there are differences in this regard; some patients are accompanied by infections, which require long-term, full-dose and combined use of antibiotics; and some patients need regular input of plasma, red blood cells, and so on. These are all factors that may increase patients’ costs. The cost of some patients can reach 700,000 yuan, or even one million. For details, we recommend that patients consult a hepatobiliary surgeon at a large hospital.