Excessive or inappropriate intake of coffee is more irritating to the stomach and may cause some damage. Coffee has the effect of refreshing the mind and improving work efficiency, but patients with gastrointestinal discomfort should not use it more often. Coffee contains tannic acid substances, which are very stimulating to the stomach and may cause an increase in gastric acid, which may cause some damage to the mucous membrane, and prolonged stimulation may cause reflux esophagitis, gastritis and gastric ulcers and other diseases. The caffeine in coffee can promote sympathetic nerve excitation, make the stomach peristalsis faster, and promote the secretion of gastric acid. The gastric acid already produced may also stimulate the secretion of more gastric acid, exacerbating the abdominal pain and bloating caused by the patient’s own gastrointestinal tract diseases, or making them recurring. If the patient has an upset stomach or is concerned about affecting the workings of the intestines, reduce the amount of coffee consumed or do not consume coffee, at least not on an empty stomach. If any discomfort occurs, please go to a regular hospital for diagnosis and treatment immediately.