Whether a liver mass of 189 millimeters is serious should be determined according to the nature of the mass, benign 189 millimeters liver mass is not serious, malignant 189 millimeters liver mass is more serious. Benign 189 mm liver mass may be liver cysts, liver hemangioma, calcified foci and other lesions, which generally do not cause obvious clinical symptoms, and only need regular observation and follow-up; if the increase in size of the mass causes abdominal distension, abdominal pain, nausea, and other symptoms, it is necessary to go to the hospital in a timely manner for consultation. Malignant 189 mm liver mass may be liver cancer, liver sarcoma, liver lymphoma and other lesions. As the 189 mm mass is large, it usually has caused obvious symptoms to the patient. If left untreated malignant liver mass has the risk of continuing to grow and metastasize, leading to symptoms such as abdominal pain, gastrointestinal bleeding, fever, anemia, etc. It can also significantly shorten the patient’s survival; therefore, malignant liver mass is more serious. When a liver mass of 189 millimeters is detected, the patient should go to the hospital in time to improve the examination, clarify the nature of the mass, and treat it according to the doctor’s guidance and recommendations.