The bumps on the body in the advanced stage of esophageal cancer may be herpes zoster, drug allergic rash or local lumps caused by bone metastasis. If the immunity of the body decreases in the advanced stage of esophageal cancer and the virus replicates in large quantities, the bumps distributed along the intercostal nerves will grow, which is actually herpes zoster, and it is necessary to cooperate with doctors to carry out antiviral treatment and anti-tumor treatment as soon as possible. If drug allergic reaction occurs in the advanced stage of esophageal cancer, the bumps on the body may be drug allergic rash, which needs to stop using drugs and cooperate with doctor for desensitization treatment if necessary. If there are lumps on the body in the advanced stage of esophageal cancer, it may be bone metastasis of tumor cells, and lumps will appear on the collarbone and neck, so it is necessary to take effective treatment measures as soon as possible. In case of lumps in late stage of esophageal cancer, it should not be neglected and it is recommended to go to hospital as soon as possible for consultation and treatment so as to control the development of the disease in time.