Alcohol is not recommended during H. pylori treatment. H. pylori infection is the cause of many digestive disorders, such as chronic gastritis and peptic ulcer. The treatment program for H. pylori is a quadruple therapy of 1 proton pump inhibitor, 2 antibiotics and 1 bismuth combination, which is commonly used as a combination of omeprazole, amoxicillin, clarithromycin, and bismuth potassium citrate. During the treatment period, not only should we take medication regularly, but also have a reasonable diet, keep a light, balanced and regular diet, avoid cold, spicy, sweet and greasy and other stimulating foods, and avoid drinking alcohol, strong tea, coffee and so on. Alcohol can damage the mucous membrane of the digestive tract and reduce the mucous membrane barrier function, and may also affect the concentration and efficacy of the drug, and is generally not recommended. People with H. pylori infection should standardize their treatment under the guidance of a doctor and eat a reasonable diet.