Patellofemoral arthritis is a chronic joint disease caused by osteophytes or cartilage degeneration. Joint pain occurs due to patellar softening, joint degeneration, cartilage wear and tear caused by chronic, progressive, long-term joint pathology. Mainly manifested as joint pain, especially exertion or weather changes pain aggravation, rest will also appear pain, morning stiffness, touch the local bone rubbing feeling. The treatment of patellofemoral arthritis mainly consists of exercises under non-weight bearing, such as swimming, cycling, quadriceps exercises. Heat therapy, acupuncture, massage can be taken. Medications include chondro-nutritional drugs such as glucosamine sulfate capsules and non-steroidal painkillers such as sodium aceclofenac. Arthroscopic debridement or joint replacement surgery may be performed if conservative treatment is not effective. Patellofemoral arthritis requires prompt medical attention if joint pain occurs. The above drugs should be used under the guidance of a doctor to avoid blind use of drugs.