Depakene is the trade name for Sodium Valproate Extended-Release Tablets.The difference between Sodium Valproate Extended-Release Tablets and Sodium Valproate Tablets is the difference in the duration of the drug’s action and the difference in the day-to-day expense. Sodium valproate extended-release tablets last longer and cost more. Sodium valproate extended-release tablets through the process of production, so that the time of action of the drug changes, drug release, absorption time is extended, once a day to ensure effective blood concentration, but the cost is higher. Sodium valproate tablets have a shorter duration of action and are taken more often in a day, requiring two to three doses a day, which is relatively easy to miss, though the cost is relatively low. Common adverse reactions to sodium valproate are characterized by diarrhea, dyspepsia, nausea, vomiting, gastrointestinal cramps, and can cause changes in the menstrual cycle. It is contraindicated in patients who are allergic to sodium valproate. Both medications are composed of sodium valproate and are used in the treatment of epilepsy to control seizures. Which preparation you need to take, you need to decide according to your actual situation and follow your doctor’s instructions.