Due to the long drug half-life of Azithromycin tablets, it usually lasts for about 72 hours, but the duration of the drug effect also depends on the individual’s sensitivity to the drug. Azithromycin is a macrolide broad-spectrum antibiotic mainly used for the treatment of upper respiratory tract infections, pneumonia caused by sensitive bacteria, oropharyngeal and middle ear infections, and other diseases. Azithromycin is metabolized slowly in the body, and the peak drug concentration in the blood can be reached after 2-3 hours of a single dose. Its blood half-life (the time it takes for the amount of drug in the body to decrease to one-half) is long, about 35-48 hours. The drug effect of azithromycin tablets lasts relatively long in the body, and a certain concentration of the drug can usually still be detected in the body 72 hours after taking the drug. However, the exact duration of drug effect after taking azithromycin tablets varies from person to person due to differences in absorption and sensitivity of the drug in each individual. The most common adverse reactions after taking Azithromycin tablets are gastrointestinal irritation symptoms, such as nausea, vomiting and epigastric pain.