There is no best way to reduce LDL cholesterol, the common method is to take statin drugs, such as lovastatin and pitavastatin. Low-density cholesterol is an important cause of hypercholesterolemia, which in turn can easily cause various cardiovascular diseases such as coronary atherosclerotic heart disease. In general, LDL cholesterol below 3.37mmol/L can be lowered through diet and lifestyle habits. It should be noted that patients with medium to high risk and patients with cardiovascular diseases need to take statins to further reduce LDL levels to the desired standard even if it is lower than 3.37mmol/L in order to reduce the risk of cardiovascular diseases. Commonly used statins include lovastatin and pitavastatin. Side effects are rare, but some patients may experience elevated aminotransferases, abdominal pain, and myositis, and in severe cases, even rhabdomyolysis, which usually recovers when the drug is discontinued. It is not recommended for patients with drug allergy or liver disease. In addition, subcutaneous injections of PCSK9 inhibitors such as iloyumab can also be used. The medication should be administered under the supervision of a physician and should not be used without authorization.