A tingling sensation from the throat to the chest, clinically speaking, may mean that the lesion occurs in the throat, esophagus, heart, lungs, mediastinum and other parts of the body. Clinically for this situation, it is recommended that the patient can go to the otorhinolaryngology, gastroenterology, cardiology, thoracic surgery and other related departments for consultation and examination in order to avoid missed diagnosis of the disease. Common types of diseases may be as follows: 1. Diseases of pharynx, some patients, such as ulcerative changes of pharynx, as well as tumors of pharynx and common hypopharyngeal carcinoma, etc., may have the feeling of discomfort in the throat and underneath the throat. If the patient has esophageal metastasis of hypopharyngeal cancer, when the patient swallows, he/she will have discomfort from throat to chest and esophagus; 2. The patient has esophageal diseases, such as some patients have reflux esophagitis, reflux gastritis and gastroesophageal acid reflux, which will lead to discomfort such as burning sensation and tingling sensation in esophagus area, which is very common in clinic; 3. Some patients suddenly have heart Myocardial ischemia, angina pectoris, etc., may radiate to this position. It is recommended that patients do electrocardiogram, cardiac enzyme spectrum and other tests to avoid the missed diagnosis of the disease. In other patients, for example, there are infections of the lungs and mediastinum, and there are mediastinal abscesses, which can lead to very obvious pain and discomfort in the esophagus in the chest area. In this case, a CT scan of the mediastinum can detect the disease.