Dead skin on the soles of the feet may be a normal physiological phenomenon, or it may be related to callus, tinea pedis and other factors. In the treatment of the general to observe the main, if necessary, can be targeted to give antifungal drug treatment. 1. Physiological factors: the skin belongs to a normal tissue structure, there is a perfect growth cycle. Generally every month or so will complete the renewal cycle, and constantly shedding dead skin, so as to maintain the normal physiological function of the skin. For this situation, generally do not need to carry out too much treatment. 2. Callus: is due to the local skin for a long time friction or extrusion and the formation of a kind of horny layer, which is also a kind of normal self-protection, no need to treat. 3. Tinea pedis: caused by peeling and fungal infections, in the treatment of anti-fungal drugs need to be selected after the peeling symptoms can be relieved, such as follow the doctor’s instructions for external ketoconazole cream, miconazole nitrate cream and so on. Due to the different causes of the disease, so the treatment may also have certain changes, the specific circumstances need to ask the doctor for an interview.