Ankylosing spondylitis may affect sex life. The impact of this type of disease on sexual life is mainly reflected in the following aspects: 1, this type of disease may make the patient’s physical quality greatly reduced, for example, the patient may have long-term fatigue, lethargy, low fever, at this time the patient is likely to have a decline in sexual ability, such as impotence, premature ejaculation. 2, may produce related joint lesions, and then make the patient is reluctant to do the lumbosacral region of the activities related to the lumbar-sacral region, such as Patients will have pain in the sacroiliac joints, lumbar vertebrae and other parts of the body. At this time during sexual life, it may induce severe pain. 3, there may be cardiopulmonary related lesions. This kind of patients may cause panic, chest pain, palpitation, dyspnea and so on due to the above mentioned lesions, which will then be unfavorable to sexual life.4. For some serious ankylosing spondylitis patients will also produce neurological related lesions, for example, the cauda equina nerve may be stimulated, which will then lead to the related perineal area symptoms, such as impotence, premature ejaculation, or have the sensation of numbness in the perineal area and other symptoms, which will then cause serious influence on the sexual life. This can have a serious impact on sexual life.