Patients with advanced heart failure are mainly diuretic with drugs, such as spironolactone, furosemide, hydrochlorothiazide and other drugs. 1 spironolactone: spironolactone belongs to the potassium-preserving diuretic, mainly used in the treatment of advanced heart failure, cardiac insufficiency triggered by sodium retention, and lower limb edema, spironolactone can act in the kidneys, interfering with aldosterone metabolism, so that the potassium ion absorption increases, with the effect of sodium diuretic, can reduce the burden on the heart, protect the cardiovascular system, and improve the cardiac function, pay attention to the monitoring of electrolytes in the process of use. 2 Furosemide: Furosemide, also known as tachycardia, is a high-performance diuretic, can reduce the reabsorption of sodium chloride, used to relieve water-sodium retention, improve the cardiac load to play a diuretic effect, can be selected under the guidance of a doctor orally or intravenously, in the use of the process of preventing the occurrence of hypokalemia, if there is a worsening of the condition, should consult a doctor in time. 3. Hydrochlorothiazide: Hydrochlorothiazide is a kind of diuretic, which can inhibit the function of renal tubules, promote the discharge of water and sodium, reduce the afterload of the heart, and alleviate the symptoms of heart failure. It can also be used in combination with deacetyl furfuracein, which is mainly used to enhance myocardial contractility and improve circulation, and the heart rate should be observed during use. If any other discomfort occurs, medical attention should be sought. When using any kind of medicine, it should be taken under the correct guidance of the doctor, so as not to aggravate the condition.