Rumbling stomach is one of the common symptoms of the digestive system, mainly caused by accelerated intestinal peristalsis, generally related to dietary factors, in addition to gastrointestinal diseases, and certain drugs. In general, excessive consumption of high-fat foods and foods containing carbonic acid are likely to cause it, and patients with gastrointestinal dysfunction, functional dyspepsia or dysbiosis of intestinal flora, acute and chronic inflammation of the gastrointestinal tract are also prone to it. There is also the occurrence of accelerated gastrointestinal motility in patients after taking certain drugs orally, and patients with visceral hypersensitivity are also prone to this condition, and these patients are usually examined without the presence of any organic lesions. In conclusion, there are many reasons for stomach rumbling, so pay attention to your diet in your daily life, develop good eating habits, and undergo colonoscopy and other related tests as well as drug interventions if necessary.