Urinary occult blood in patients with renal insufficiency can be seen in glomerulonephritis, urinary tract infection, urinary tract tumor and other diseases. 1. Glomerulonephritis: it can be manifested as hematuria, proteinuria, hypertension and edema. As the disease progresses, it leads to renal insufficiency, so patients with renal insufficiency can appear urinary occult blood. 2. Urinary tract infection: common cystitis, pyelonephritis, etc., the inflammation stimulates the bladder mucous membrane erosion and bleeding, causing urinary occult blood positive. If the condition is prolonged and develops into chronic pyelonephritis, it may lead to renal insufficiency. 3. Urological tumors: renal tumors can also cause painless hematuria when invading renal calyx and renal pelvis. Long-term invasion of renal parenchyma can eventually lead to renal insufficiency. Patients with renal insufficiency may also have other causes of urinary occult blood, it is recommended to go to regular hospitals in a timely manner, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment under the guidance of the doctor.