Down’s syndrome is characterized by a low nasal bridge, wide eye spacing, small eye fissures, upward facing outer corners of the eyes, small ears, and an open mouth with an outstretched tongue. In addition to the specific facial features, the disease is often combined with mental retardation, which is a chromosomal lesion. There is no effective treatment for this disease, but early training and education is the main way to improve the baby’s intellectual development and physical ability. Prenatal screening and diagnosis should be actively performed during pregnancy to confirm the diagnosis as early as possible and give the necessary symptomatic treatment.