If a patient experiences a burning sensation in urination, the first cause to consider is a UTI. From the perspective of the cause, UTIs can be divided into gonococcal UTIs and non-gonococcal UTIs. The actual UTI is an acute inflammation caused by gonococcal infection of the urethra. Generally speaking, the clinical symptoms of gonococcal urethritis are more obvious, and the purulent discharge from the urethra is more viscous. The pathogen of non-gonorrheal urethritis is usually mycoplasma or chlamydia, clinically Mycoplasma solium and Mycoplasma humanum are the main ones, treatment is usually recommended to choose tetracycline antibiotics to treat, you can choose minocycline or doxycycline. In female patients, it is also possible to have burning sensation in urination due to urinary tract infection. However, urinary tract infection is a very common disease for women, and usually the causative organisms are mainly gram-negative bacteria, so it is usually recommended to choose levofloxacin or fosfomycin as the first choice of treatment.