A common cause of burning-like sensation in the calves is acute transient muscle inflammation, which occurs after excessive exercise, such as prolonged walking, prolonged running, and repeated jumping movements, which can cause subtle muscle damage, resulting in exuded fluid or even blood leaking from the muscle interstices. The blood vessels may dilate after exercise, and the calves may become slightly swollen or feel swollen in the calves, which may manifest as a burning sensation in the calves, and the more severe the muscle damage and inflammation, the more pronounced the burning sensation will be, which may also turn into a painful sensation. There may also be a bacterial infection or nerve inflammation in the calf. The infection in the leg may manifest as a burning-like sensation, and localized redness and swelling may occur, while the nerve inflammation may only appear as a burning sensation.