The pain in the middle of the rib cage in the thoracic region due to prolonged sitting may be related to costochondritis, thoracic spine lesions, chronic injuries, acute coronary ischemic syndrome and other conditions. It is recommended to go to the hospital for consultation, and if necessary, use ibuprofen and other drugs to relieve pain. 1, costal chondritis: chronic strain on the ligaments of the thoracic rib joints due to sedentary, there may be pain in the middle of the ribs in the chest, manifested as dull pain, hidden pain, and occasionally pinprick-like pain, the pain site is relatively fixed, and the pain increases when pressed; 2, thoracic spine lesions: degenerative lesions of the thoracic spine due to age and other factors, or When thoracic spine lesions caused by improper sitting posture, pain may radiate to the abdominal wall and chest wall, sometimes mistaken for angina pectoris, and pain in the middle of the chest ribs may occur after prolonged sitting; 3. Chronic injury: prolonged sitting may lead to chronic injury to the muscles and ligaments around the spine, which in turn produces pain, sometimes manifesting as pain in the middle of the chest ribs after prolonged sitting, and the pain may increase after exercise; 4. Acute coronary ischemic syndrome: In a sedentary state, prolonged inactivity may form venous thrombosis of the lower extremities, which may result in transient ischemia due to the dislodgement of the thrombus, which flows down the blood circulation to the coronary arteries, manifesting as pain in the middle of the ribs in the chest; 5, other factors: the presence of gastritis, cholecystitis, stress ulcers and other digestive system diseases may also produce stomach bloating, stomach pain and other sensations, and sometimes the pain will radiate to the chest, manifesting as sedentary chest Pain in the middle of the rib cage. When there are diseases such as intercostal neuritis and pleurisy, inflammatory factors may stimulate painful reactions in the pleural wall, which may manifest as pain in the middle of the ribs in the sedentary chest. In addition, if there has been a trauma to the chest wall, such as a violent impact or a sudden slip, the symptom of pain in the middle of the ribs in the sedentary chest may occur. Most people who experience pain in the middle of the ribs in the chest after sitting for a long time are able to relieve the local symptoms after rest and activity. When the pain symptoms cannot be relieved, it is recommended to go to the hospital in time to improve the electrocardiogram, three heart attacks, lung CT and other examinations to exclude critical diseases that cause life-threatening injuries, such as myocardial infarction.