In recent years, cancer has become one of the major diseases that endanger the society and human health, and it has brought great pain and distress to human beings. In order to reduce the incidence of cancer, we human beings should master about the pre-mortem symptoms of advanced cancer: 1.Unexplained wasting, weakness, irregular pain in the upper abdomen, decreased appetite, especially aversion to meat food. 2.Non-pregnant and breastfeeding women with nipples running or able to squeeze out fluid. 3.A gradually increasing lump in any part of the body such as breast, neck or abdomen. 4.Dry cough, blood in the sputum, chest tightness and chest pain that cannot be cured for a long time. 5.Women of middle age or above have small amount of vaginal bleeding after sexual intercourse, or usually have irregular vaginal bleeding, or menstruation again after several years of menopause, and leucorrhoea increases significantly. 6.Progressively deepening jaundice and epigastric mass without abdominal pain. 7.Faster enlargement of the liver with pain in the liver area. 8.Unexplained painless hematuria. 9.Skin ulcers that do not heal for a long time. 10.Sudden enlargement of the mole, accompanied by burning, itching, breaking, painful bleeding or loss of hair on the mole. 11.Recurrent fever and persistent dental bleeding, subcutaneous bleeding and progressive anemia. 12, Recurrent unexplained high fever. 13.White spots on the oral mucosa, or female vulva or male penis glans, and rapidly expanding and itching discomfort. 14.Progressive weakness of both lower extremities, abnormal sensation, movement disorder or incontinence of urine and stool sometimes. 15.Fracture of large bones such as femur and humerus without obvious external force. 16.Sensation of foreign body obstruction, tingling sensation behind the sternum when eating and swallowing or slow passage of food. 17.Nasal congestion, frequent small amount of nasal bleeding or blood in the nose, accompanied by migraine, dizziness, tinnitus and swollen lymph nodes felt in the upper part of the neck below the earlobe in the anterior and posterior parts. 18.Changes in bowel habits, or frequent alternation of diarrhea and constipation, or stools often with pus and blood, or stools become thin and flat. 19. Gradually increasing headache with sudden onset of transient visual disturbance and vomiting.