The skull is like a barrier, with the protection of the skull, the brain tissue can function normally. However, a traffic accident or a falling object can cause skull damage, and after skull damage, the patient’s appearance is ruined, the quality of life is reduced, and health problems will follow, so we can’t be careless. The correct way to deal with cranial defects is to do cranial repair surgery, which is a very common surgery in neurosurgery, and after thousands of years of development, it is now technically quite mature, and the cranial repair materials have also undergone continuous improvement and innovation, becoming more and more advanced. How many types of cranial repair materials are available? In the early days, they were autologous bone, animal bone, bone cement and plexiglass, but they were slowly eliminated due to various unsuitability. At present, titanium mesh material is more used clinically, which has some progress compared with various early materials, but titanium mesh material also has many shortcomings, such as insulation, strength, histocompatibility, etc. There are some gaps compared with autologous cranial bone, easy to be infected after surgery, and may also have rejection reaction, etc. Because of these defects, the emergence of peek material has received great support and affirmation. peek material is a very safe and advanced polymer material, with good tissue compatibility, three-dimensional shaping, excellent protective properties, and good postoperative recovery, and is a good choice for cranial repair material. We use peek material to perform skull repair surgery for patients with skull defects. The team has continued to research and explore, and has successfully integrated the concept of aesthetic plastic surgery into the surgery, and has carried out comprehensive PEEK cranial bone repair and plastic surgery, and the post-operative results are very natural and beautiful.