Scrotal cracking may be caused by skin dehydration, scrotal eczema, scrotal fungal infections and other factors related to the patient should be based on different reasons, under the guidance of the doctor to choose the appropriate treatment drugs, make including urea cream, halomethasone cream, fluconazole ointment and so on. 1. Skin dehydration: when the patient is in a dry environment, or serious sweating after failing to timely replenish water may cause dry skin dehydration, thus appearing scrotal skin cracking, peeling and so on, the patient can be under the guidance of the doctor to use urea cream, vitamin E cream, polysulfonic acid mucopolysaccharides cream and other drugs for treatment. 2. Scrotal eczema: For patients with scrotal eczema causing skin cracking, glucocorticoid drugs such as dexamethasone cream, Hasinide cream, halometasone cream, etc.; immunosuppressants such as tacrolimus ointment, pimecrolimus cream and other medications can be used for treatment to improve the symptoms under the guidance of a doctor. 3. Scrotal fungal infections: for scrotal fungal infections caused by skin cracking patients can follow the doctor’s instructions to use antifungal drugs, such as fluconazole ointment, ketoconazole cream, terbinafine cream and other drugs for treatment. It is recommended that patients strictly follow the doctor’s instructions, do not change the dose of drugs or private abuse of drugs, in life to develop good habits, pay attention to personal hygiene, avoid scratching the affected area, regular review.