Cardiovascular accidents are the main cause of death and disability in diabetic patients. In winter, risk factors that cause cardiovascular accidents in diabetes such as blood sugar fluctuation, hypertension, hyperlipidemia, enhanced platelet aggregation and accelerated blood clotting are more significant, and the high incidence of infectious diseases such as cold and flu in winter makes these risk factors more prominent. Therefore, diabetic patients should pay more attention to the control of these risk factors in winter to help reduce the occurrence of cardiovascular and cerebrovascular accidents. First of all, in winter, due to the low outdoor activities, coupled with the cold stimulation of the body to increase the secretion of blood glucose hormone, diabetic patients generally show elevated blood glucose. After the blood glucose rises, some patients will show uncontrollable hyperglycemia or recurrent hypoglycemia because they have not received proper blood glucose regulation treatment. Both hyperglycemia and hypoglycemia make patients’ blood glucose fluctuate more, and blood glucose fluctuation can initiate pathophysiological reactions harmful to the heart, brain and kidney such as oxidative stress, especially hypoglycemia can directly produce serious damage to the heart and brain. Therefore, diabetic patients should strengthen the monitoring of blood glucose in winter and adjust the intake of diet according to the change of exercise condition; poorly controlled blood glucose should adjust the treatment plan under the guidance of a specialist, and never adjust the hypoglycemic treatment drugs by themselves. Various metabolic disorders in diabetes can easily cause damage to the heart, brain, kidneys and other important organs, and if combined with hypertension at the same time, it is like adding fuel to the fire and destroying these important organs even faster. Many large clinical studies have confirmed that good control of blood pressure in diabetic patients has a greater effect on reducing macrovascular complications such as diabetic cardiovascular and cerebrovascular than good control of blood glucose, and is more beneficial in relieving diabetic cardiovascular and cerebrovascular complications. In winter, the blood pressure of patients is significantly higher than in summer due to increased secretion of blood pressure-raising hormones and peripheral vasoconstriction stimulated by cold. For every 1°C drop in temperature, systolic blood pressure rises 1.3 mm Hg and diastolic blood pressure rises 0.6 mm Hg. Therefore, diabetic patients should strengthen the measurement of blood pressure in winter and adjust the dose and type of blood pressure-lowering drugs in time, preferably to control blood pressure below 140/85 mm Hg. Abnormalities in the diabetic lipid profile are one of the important risk factors for diabetic macroangiopathy. Abnormal lipid profile is characterized by high triglyceride, high cholesterol, high LDL and low HDL. Correcting lipids means to reduce the high harmful lipids, i.e. triglycerides, high cholesterol and LDL, to the desired level, especially to control LDL below the target level and to raise the low beneficial lipids, i.e. HDL, to the appropriate level. Large clinical studies such as 4S and cardioprotection trials have demonstrated that long-term application of lipid-regulating therapy can significantly reduce cardiovascular and cerebrovascular accidents. However, inappropriate supplementation and excessive intake of fats and oils in diabetic patients with reduced activity in winter often aggravate lipid metabolism disorders. Therefore, diabetic patients should pay attention to changes in blood lipids in winter, choose appropriate lipid-regulating drugs, and be sure to control LDL levels to the target target values recommended by their specialists. The blood clotting rate, platelet aggregation function and blood fibrinogen content are significantly higher in diabetic patients than in normal people, which means that diabetic patients are more likely to form blood clots than normal people. The above abnormal blood clotting phenomena are more prominent in diabetic patients with reduced activity and slow blood flow in winter. This is also an important reason why diabetic patients are prone to cerebral and myocardial infarction in winter. For this reason, diabetic patients should choose appropriate thrombosis prevention drugs under the guidance of their doctors and insist on long-term medication, rather than short-term infusion “blood vessel” treatment. (1) Anti-platelet drugs such as aspirin, which can significantly reduce the incidence of myocardial infarction and cerebral infarction and completely prevent transient ischemic attack (TIA) in diabetic patients by taking 100-300mg of aspirin daily. (2) Anticoagulant drugs such as Warfarin can block the utilization of vitamin K and anticoagulate. Prolongation of prothrombin time can occur 12-18 hours after administration. A trial showed that diabetic patients with warfarin 24-63 months after the mortality rate due to complications such as myocardial infarction and cerebral thrombosis was significantly reduced. The recurrence rate of myocardial infarction was reduced by 43%. The above-mentioned blood glucose, blood pressure, blood lipids and high blood clotting are the main risk factors for cardiovascular and cerebrovascular events in diabetic patients in winter, and diabetic patients should pay great attention to these risk factors. Of course, the focus of risk factors is different for each diabetic patient, so it is best to develop a treatment plan to prevent cardiovascular accidents in winter under the guidance of your doctor, so that you can safely survive the dangerous season with a high incidence of cardiovascular disease.