Increased neonatal cardiac enzymes suggest the presence of cardiomyocyte damage, and the cardiac enzyme profile usually returns to normal after 7-10 days of treatment with drugs that nourish the myocardium. Increased neonatal cardiac enzymes can be caused by neonatal hypoxia, rheumatic heart disease, viral myocarditis and other diseases. If neonatal cardiac enzymes are slightly elevated and the baby has no obvious symptoms, the cardiac enzymes usually return to normal after 7-10 days with sufficient rest and enhanced care, and with the application of nutritive cardiac drugs, such as sodium glycoside diphosphate, vitamin C, creatine phosphate, and so on. For newborns with markedly elevated cardiac enzymes, which may indicate severe myocardial injury, myocardial nutritional drugs may need to be applied for half a month to a month or even longer before the baby can achieve healing. Babies with elevated cardiac enzymes need to go to the neonatal hospital in time to avoid delays if they have weak mental state, weakness, pallor and other signs of cardiac decompensation.