In the treatment of essential hypertension, nifedipine controlled release tablets and enalapril can be used together. However, not all patients with high blood pressure can take these two drugs at the same time, and they should be used under the guidance of professional doctors. 1. Nifedipine controlled release tablets are calcium channel blockers. It is used for the treatment of hypertension and chronic stable angina. Its common adverse reactions include peripheral edema, dizziness, headache, fatigue, facial flushing, transient hypotension, palpitations (rapid heartbeat, often accompanied by panic), chest tightness, nausea, constipation, diarrhea, gastrointestinal spasms, abdominal distension, insomnia and so on. Contraindications to the drug are: hypersensitivity to nifedipine or any of the components of the product, patients with cardiogenic shock, patients taking rifampicin, pregnant and lactating women are prohibited. 2. Enalapril is an angiotensin converting enzyme inhibitor. It is used for the treatment of essential hypertension. Its common adverse reactions include dizziness, headache, drowsiness, dry mouth, fatigue, epigastric discomfort, nausea, palpitations (rapid heartbeat, often accompanied by panic), chest tightness, irritating dry cough, rash, proteinuria and so on. Contraindications to the drug are: hypersensitivity to enalapril or other ACEI drugs, previous history of angioneurotic edema, renal artery stenosis (bilateral or unilateral renal patients), patients with aortic or mitral stenosis, hypertrophic cardiomyopathy, patients with primary aldosteronism, patients with primary hepatic disorders or hepatic failure, and so on. As you can see, there is no contraindication to the use of the two drugs, and they are often used in combination for the treatment of essential hypertension. Nifedipine controlled release tablets and enalapril should be used under the guidance of a professional doctor, do not blindly self-medication to avoid adverse consequences.