Voice loss with yellow sputum may be caused by tracheitis, pneumonia upper respiratory tract infection, chronic pharyngitis, acute laryngitis and so on. 1. tracheitis: when affected by biological, physical and chemical stimuli or allergies and other factors, there will be inflammation of the mucous membrane of the trachea, resulting in patients with loss of voice with yellow sputum, mainly manifested in coughing, coughing up sputum, serious patients will have wheezing, shortness of breath and other symptoms. 2. Pneumonia upper respiratory tract infection: loss of voice with yellow sputum may be caused by pneumonia upper respiratory tract infection caused by severe coughing, common pathogens for the virus, can be secondary to a small number of bacterial infections, the patient will appear coughing, hoarseness sneezing, nasal congestion, sore throat, fever and other symptoms. 3. Chronic pharyngitis: the disease is mainly related to the patient’s bad habits, nasopharyngeal diseases, so that the patient appears voice loss with yellow phlegm, accompanied by pharyngeal foreign body sensation, burning sensation. 4. Acute laryngitis: the patient’s voice loss of yellow sputum is considered to be caused by acute laryngitis, mainly due to infection, excessive use of voice, stimulation and other factors resulting in acute laryngeal mucosal catarrhal inflammation, the patient manifested hoarseness, coughing, sore throat and so on. It is recommended that patients go to the hospital in time, under the diagnosis of the doctor, according to the patient’s condition, to take targeted treatment.