Imipenem is a thiamphenicol antibacterial drug with carbapenem ring, a broad-spectrum antibiotic, used for the treatment of various systemic infections, bacteremia and sepsis caused by sensitive bacteria, especially for mixed infections and empirical treatment of infections of unknown cause. The antibacterial effect and stability of Imipenem is better than that of Thiamphenicol, with a broader antibacterial spectrum and stronger antibacterial effect, but the dosage of this product may vary in different dosage forms and specifications, and medical advice is required for the use of this drug. Imipenem has poor stability when used alone, so it is often used together with cilastatin in clinical practice, which can protect imipenem from destruction in the kidney and reduce its nephrotoxicity without affecting the efficacy of imipenem. Adverse reactions to imipenem include nausea, vomiting, and erythema, and this drug is contraindicated in patients who are allergic to the active ingredients of the drug, or in patients with pre-existing severe shock or heart block. In addition, it has not been clarified whether this product can be secreted through breast milk, and it should be used with caution in lactating women. If use is required, discontinuation of the drug or suspension of breastfeeding should be an option.