Perianal abscess after anti-inflammatory appeared local hard and painful, may be inflammatory mass, scarring mass and other reasons. Generally, the clinical use of surgical radical treatment, late antibiotic anti-inflammatory, and symptomatic treatment. 1. Inflammatory mass: perianal abscess is a purulent disease caused by the infection of soft tissue and interstitial space around the anal canal and rectum. The common cause is due to repeated episodes of inflammation of the anal sinus, because the pus cavity has an infected internal opening, part of the combined anal fistula. After anti-inflammatory drugs to give anti-infection treatment, the infection foci still exist, the formation of inflammatory masses, the clinical symptoms of hard and painful. 2. Scarring mass: when the pus in the abscess cavity after the outflow or anti-infective treatment with anti-inflammatory drugs, the infected tissue healing in the first formation of fibrinoid changes, the formation of local hard lumps, such as abscess infection is not completely absorbed, will be combined with local pain. When the inflammation is completely absorbed and the tissue is repaired, the lump will disappear and the tissue will become soft. If there is still a lump, pain and other discomforts after anti-inflammatory perianal abscess, it is recommended to seek medical treatment as soon as possible to avoid delaying the condition.