The difference between rheumatoid nodules and rheumatoid nodules lies in the etiology and clinical symptoms. 1. Etiology (1) Rheumatoid nodules: the formation of rheumatoid nodules is related to rheumatic fever and rheumatoid arthritis, which are caused by inflammation of the joints. (2) Rheumatoid nodules: Rheumatoid nodules are subcutaneous nodules formed by the characteristic changes of rheumatoid arthritis. 2. Clinical symptoms (1) Rheumatoid nodules: mainly manifested as slightly hard, painless nodules located in the subcutaneous tissue of the joint extensor surfaces. Usually occurring in the wrist, elbow, knee and other parts of the joints, no adhesion with the skin, no redness or swelling of the surface skin, the nodules may affect the flexion and extension of the joints, affecting the activities. (2) Rheumatoid nodules: the size of the nodules is about 0.2~3 cm, mostly round or ovate, hard to touch without pressure pain, and symmetrically distributed. Most of them are located in the subcutaneous part of the joints and pressure areas, such as the extension surface of the forearm, Achilles tendon, bursa, etc. Nodules can be found in the pericardium, pleura, and eyes, etc. The presence of nodules suggests rheumatoid disease. Their presence suggests rheumatoid activity. It is recommended that patients with rheumatoid nodules or rheumatoid nodules should go to the hospital in time to find out the cause of the disease and receive symptomatic treatment under the guidance of a professional doctor.