Chronic obstructive pulmonary disease (COPD) is a chronic bronchitis characterized by airway obstruction, mostly accompanied by emphysema. If uncontrolled, further development will cause pulmonary heart disease, respiratory failure, and in more severe cases, pulmonary encephalopathy, electrolyte disorders, acid-base imbalance, cardiac arrhythmia, gastrointestinal bleeding, and eventually death due to respiratory failure. Before the end of life, there is a tendency to have cyanosis of the lips, blurred consciousness or complete loss of consciousness, sweating, coarse breathing sound, phlegm sound, dyspnea, etc. There are also symptoms of circulatory failure, a significant increase in heart rate and a significant drop in blood pressure when measuring the heart rate.