Down screening refers to Down’s syndrome screening. Failure to pass Down’s syndrome screening may be related to errors, the pregnant woman’s own reasons, fetal abnormalities, etc., which may require re-checking, strengthening the test, or abandoning the fetus. 1. Error: Failure to pass the Down’s syndrome test may be caused by errors in the results. The data provided by the pregnant woman during the Down’s syndrome test, such as gestational week, age, weight, etc., do not match the actual situation, which affects the accuracy of the results of the Down’s syndrome test, and requires re-examination. 2. Pregnant women’s own reasons: Down’s syndrome screening failed may be related to the age of pregnant women, pregnant women’s health status is not very good and other factors, it is recommended that pregnant women should not be too nervous, you can do non-invasive DNA testing for further examination. 3. Fetal anomalies: Down’s syndrome screening failed may be the fetus really have chromosomal abnormalities, may suffer from Down’s syndrome, this time can be considered in conjunction with the specific circumstances of the termination of pregnancy. Down’s screening is not out of date pregnant women do not be too nervous, under the guidance of the doctor to deal with the actual situation, it is recommended that pregnant women Down’s screening should go to a regular hospital, and provide accurate data for the examination.