The treatment options for prostate cancer bone metastasis include bone-modifying drug therapy, anti-tumor therapy, analgesic therapy, radiation therapy, surgery and other measures, and there is no best way. 1. Systematic treatment (1) Bone-modifying drug therapy: including the use of zoledronic acid, disulfiramab and other drugs. (2) Anti-tumor therapy: endocrine therapy with drugs such as goserelin, chemotherapeutic drugs such as cisplatin, and targeted drugs such as bevacizumab. (3) Analgesic treatment: according to the degree of cancer pain, different levels of analgesic drugs such as Tramadol and morphine can be chosen. 2. Local treatment (1) Radiation therapy: radionuclide external irradiation such as Radium 223 can be used. (2) Surgical treatment: Surgical interventions such as symptomatic fracture fixation, replacement and nerve relaxation can be performed. (3) Interventional therapy: radiofrequency ablation can be used. The treatment of bone metastasis of prostate cancer requires the comprehensive use of various treatments and the adjustment of the program according to the condition, and what is suitable for the condition is the best. All the above drugs should be applied under the guidance of doctors.