There are acute purulent sinusitis and chronic purulent sinusitis, which are acute and chronic purulent inflammation of the sinus mucosa. Clinically, chronic purulent sinusitis is the most common. Patients with acute sinusitis, during acute attacks, pay proper attention to rest and light diet to avoid complications. After identifying the causative organism, choose sensitive antibiotics. For those who fail to identify the causative organism, choose broad-spectrum antibiotics, with cephalosporin antibiotics as the first choice. For those who clearly have anaerobic bacterial infection, use anti-anaerobic drugs such as metronidazole at the same time. Oral nasal mucus pro-discharge agents, such as myrtle oil. Local saline cleansing of purulent nasal secretions to restore the function of nasal mucosal cilia movement; temporary nasal mucosal decongestant nasal spray for severe nasal blockage; nasal spray with nasal hormonal nasal spray. After the nasal symptoms disappear, continue to use nasal hormone-based nasal spray for two weeks. In chronic purulent sinusitis, the general course of drug therapy is three months. The main medications include: nasal hormonal nasal sprays, such as mometasone furoate nasal spray and budesonide nasal spray; mucus promoters, such as standard myrtle oil and Oronema; and small doses of macrolide antimicrobials. If the sinus opening is obstructed or if there are nasal polyps, surgical treatment is required. Surgery requires nasal polyp removal plus functional opening of the sinus orifice under nasal endoscopy to restore the normal motor function of the mucosal cilia in the nasal cavity and sinuses. Chronic purulent sinusitis is difficult to cure. When acute purulent sinusitis strikes, you need to visit the otorhinolaryngology department in time to be treated under the guidance of a doctor and completely cured in the acute stage.