A 45-year-old female patient with mild cerebral atrophy can be relieved by medication, physical therapy and rehabilitation training. 1. Medication: When patients suffer from neurodegenerative diseases and immune diseases, which may cause brain atrophy, they can be treated with neuroprotective and immunomodulatory drugs under the guidance of doctors. 2. Physical therapy: patients with mild cerebral atrophy can be treated with physical methods such as transcranial magnetic stimulation and ultrasound physiotherapy, or with massage and acupuncture. 3. Rehabilitation training: Some patients with cerebral atrophy may have language and physical function disorders, which can be alleviated through language rehabilitation training and physical function training. There are other ways to treat mild cerebral atrophy in 45-year-old female patients, and patients should seek timely medical help from doctors for diagnosis and treatment.