It is recommended that patients with connective tissue disease check the anti-nuclear antibody spectrum, autoimmune antibodies, blood sedimentation, rheumatoid factor, C-reactive protein blood routine, urine routine and other indicators. Connective tissue disease is a group of multi-system, multi-organ involvement of autoimmune diseases, including systemic lupus erythematosus, rheumatoid arthritis, polymyositis / dermatomyositis, polyarteritis nodosa, giant cell arteritis, desiccation syndrome, etc., connective tissues for the stability of the human body’s internal structure, the limbs of the normal activities of the body play an important role in the long course of the disease, complexity of the disease is the basic characteristics of the disease. The diagnosis of this type of disease is relatively complex, anti-nuclear antibody spectrum, autoimmune antibodies, blood sedimentation, rheumatoid factor, C-reactive protein blood routine, urine routine and other auxiliary tests can provide diagnostic clues. It is recommended that patients who need to check for the presence of connective tissue diseases go to the rheumatology and immunology departments of regular hospitals for detailed consultation.