Bleeding from a puppy bite requires rabies vaccination, as well as anti-rabies virus immunoglobulin. Rabies is caused by infection of the body with the rabies virus, and the rabies virus is mainly found in the saliva of dogs and cats, and bleeding from a puppy bite indicates that the saliva of the puppy may be contaminated with the wound, so it is necessary to receive rabies vaccination. First of all, after being bitten by a puppy bleeding must be the first time to deal with the wound, with running water, soap and water to the wound for a thorough rinse, is conducive to the removal of the virus, greatly reducing the risk of infection. After treatment, rabies vaccination should be carried out as soon as possible. Since there is already bleeding, it is a tertiary exposure to the rabies virus, so it is also necessary to vaccinate with anti-rabies virus immunoglobulin for emergency prevention.