Big toe nails growing into the flesh belong to ingrown toenails, which can be relieved by nail trimming, medication and surgery. 1. Trimming toenails: You can soak your toenails in warm water every night to soften them sufficiently, then use pointed scissors to cut off the toenails embedded in the tissues, and if you can’t do it at once, you can trim them several times. 2. Medication: If the bunion grows into the flesh, and if there is localized swelling, pain and other inflammatory manifestations, consider the occurrence of inguinitis, and the need for anti-infective treatment, you can orally take levofloxacin, cefixime and so on. 3. Surgery: If the symptoms are not relieved by trimming the bunion toenail and medication, surgery is needed to remove the toenail and grow a new one. If the symptoms are not relieved by trimming the big toe nail and medication, surgery is needed to remove the nail and regrow a new one. Medications should be used as prescribed by your doctor.