Itchy and bloody discharge from the lips at night may be caused by vulvovaginal pseudomycosis, vulvar sclerosing moss, cervicitis and other diseases. 1. Vulvovaginal pseudomycosis: Vulvovaginal pseudomycosis is caused by pseudomycosis infection, patients will have symptoms such as vulvar itching, vulvar redness, swelling, increased vaginal discharge, and some patients will have erosion or superficial ulcers. As a result, patients may have itching on both sides of the external lips at night and discharge with blood. 2. Vulvar sclerosing moss: Vulvar sclerosing moss is caused by heredity, autoimmune disease, sex hormone deficiency and other factors. The main symptoms of patients are vulvar itching, subcutaneous bleeding, local pigmentation for white patches, pimples, etc., so patients will have the phenomenon of itchy and blood secretion at night on both sides of the lips. 3. Cervicitis: cervicitis is due to Chlamydia trachomatis and other pathogenic infections, the patient will have vulvar itching, increased leukorrhea, vaginal bleeding and other manifestations, so the patient will have itchy external lips at night and the secretion of the symptoms of blood. When patients have symptoms of itchy external lips and blood secretion at night, they should consult a doctor in time and follow the doctor’s instructions.