The correct dosage of prednisone is generally related to the disease and individual differences, it is recommended that patients follow the doctor’s instructions to take, do not blindly use the drug. Prednisone has anti-inflammatory and anti-allergic effects, but the specific dosage of the drug needs to be selected according to the disease and individual differences, do not blindly increase or decrease the drug. For autoimmune diseases such as systemic lupus erythematosus, nephrotic syndrome, etc., can be given 40-60mg per day, and for allergic diseases such as drug dermatitis, urticaria, etc., can be given 20-40mg per day of prednisone. If it is needed to prevent organ transplantation rejection reaction, it is usually started to take 100mg orally per day 1~2 days before the operation, and then changed to 60mg per day one week after the operation. For the treatment of acute leukemia and malignant tumors, it can be given 60~80mg orally per day. Prednisone should be used with caution or prohibited in pregnant women, and should be used with caution in viral infections. After the occurrence of adverse reactions, stop the drug and seek medical attention.