Neutral pen oil composition is mainly chemical substances, if eaten inside the gastrointestinal tract, it shows symptoms such as abdominal pain, diarrhea, nausea and vomiting. If it irritates the throat or trachea, it will cause dry throat, sore throat, irritating cough, and may also induce an asthma attack. If it causes laryngeal edema and pulmonary edema, it will show respiratory distress and is life-threatening. After eating into the gastrointestinal tract, if absorption in the gastrointestinal tract occurs and spreads to organs and tissues throughout the body through the blood, it will affect the organs and tissues metabolism and abnormal function. If the central nervous system is invaded, dizziness, headache, nausea, vomiting, and in severe cases, coma, shock, and central respiratory depression may occur, resulting in life-threatening effects. If the liver and kidneys are affected, jaundice, weakness and poor appetite may occur as a result of liver and kidney damage. If the kidney function is affected, symptoms such as hematuria, proteinuria, and general edema may occur.