The incidence of colorectal cancer is closely related to the change of lifestyle and unreasonable dietary structure. With the change of people’s lifestyle and dietary structure, the incidence of colorectal cancer will further increase. Since colorectal cancer lacks early symptoms, which leads to higher mortality rate, prevention is the best method. 1.Colorectal can be prevented and screening can reduce its incidence and death rate By establishing a standardized colorectal cancer education system, establishing and strengthening the awareness of colorectal cancer prevention and treatment and the concept that colorectal cancer can be prevented.WHO’s view: 1/3 of cancers can be completely prevented, 1/3 of cancers can be cured through early detection, 1/3 of cancers can be treated scientifically to prolong patients’ lives and improve survival quality. Colorectal cancer undergoes the process from normal mucosa, atypical hyperplasia, adenoma to cancer, i.e., there is a benign development process of up to 5-10 years before becoming cancerous, which provides a favorable time for colorectal cancer prevention and early diagnosis. Although most patients have no obvious symptoms in early stage, lesions from atypical hyperplasia, adenoma to cancer process can be detected through screening. 2.Strengthen education and improve the compliance of screening patients The main problems of colorectal cancer screening are the cost and the compliance of screening patients, such as endoscopy, which is often refused by patients due to certain discomfort and pain. Therefore, in order to improve the compliance of screening patients, it is necessary to pay attention to the promotion strategy and communication skills, especially for the susceptible and high-risk groups, so that the screening patients can realize the necessity and importance of various examinations and the serious consequences of delayed diagnosis and treatment. 3. Seek support from multiple channels to promote regional colorectal cancer screening Whether colorectal cancer screening is included in the planning of local government health service system, whether it is included in the scope of project fund screening, the pre-screening education strategy and strength, and the compliance of screening patients, most of the regions and populations in China have not yet been included in screening, which is related to the national situation of China, and it is a slow process to improve this situation. This is related to our national situation, and improving this situation is a slow process. Therefore, an effective strategy is: the national level should pay attention to colorectal cancer, pay high attention to colorectal cancer from the policy perspective, and increase the investment in colorectal cancer prevention and treatment. Regional medical and health institutions should actively seek support from various funds or programs to implement colorectal cancer screening for susceptible or high-risk populations in their regions, so that they can contribute to the health of regional populations and at the same time grasp first-hand important data on the incidence of colorectal cancer in their regions, which can provide reference for regional colorectal cancer prevention and treatment strategies. Incorporate relevant elements of colorectal cancer screening, especially endoscopic means, into the health checkups of susceptible or high-risk people aged 40 to 50 years or older. Through multiple efforts, the susceptible or high-risk groups will actively formulate colorectal cancer prevention programs and regularly take the initiative in targeted physical examinations or actively participate in colorectal cancer screening programs. 4. Multi-form and multi-combination routine examinations to promote early diagnosis and treatment of colorectal cancer Health education is a necessary means to enable patients with early colorectal cancer or precancerous lesions to detect the disease in time and improve the prognosis with early treatment. In addition to increasing colorectal cancer prevention education, we advocate proactive multiform prevention and early diagnosis practices for colorectal cancer high-risk susceptible people. Most of the diagnostic tools for colorectal cancer screening are simple and easy to use, including fecal occult blood test, rectal palpation, fiberoptic sigmoidoscopy, fiberoptic total colonoscopy and dual gas-barium imaging, which are completed in most primary hospitals, with fiberoptic colonoscopy being the gold standard. Screening can be preventive or to rule out suspicious symptoms. About 75% of colorectal cancers in China are rectal cancers, and about 70% of rectal cancers are low to medium rectal cancers located below the peritoneal reflex, which can mostly be detected by rectal finger examination. Clinically, we can often see that many patients found positive fecal occult blood test, but they can further perform rectal finger examination and fiber colonoscopy in time; or patients with blood in stool mistakenly think that hemorrhoids are bleeding and do not perform anal finger examination and further endoscopy, which delays the best treatment time. Therefore, in the medical checkups or outpatient clinics for people over 40 years old who are highly susceptible to colorectal cancer, fecal occult blood test and rectal finger examination should be included as routine; whenever a patient has symptoms such as blood in stool, change in stool habit or trait, rectal finger examination, fiber colonoscopy and air-barium double imaging should be performed; for the very high-risk groups such as hereditary colorectal cancer, familial adenomatous polyposis and melanotic polyposis, the screening age should be moved forward to For adolescents, the frequency of screening should be increased. In conclusion, the high growth of colorectal cancer incidence and death rate in China has made the whole colorectal cancer prevention and treatment face great challenges. With the popularization of colorectal cancer prevention and education, the increase of government attention and investment, the adjustment of medical and health prevention and treatment strategies, the popularization of colorectal cancer screening and the enhancement of public awareness of colorectal cancer active prevention and treatment, the current situation and existing problems of colorectal cancer in China will be improved.