We often see some Parkinson’s disease patients with serious expressions, few smiles, a little anxious and restless, especially when talking about their condition, it is difficult to control their emotions, tears, depression, and even extreme thoughts, a “life is better than death” feeling. In fact, in addition to suffering from movement disorders, a significant number of patients also have varying degrees of anxiety and depression. Studies have found that depression in Parkinson’s disease patients is usually mild to moderate, and about 40% of Parkinson’s disease patients will experience depressive symptoms during the course of their disease, with 25% of them depressed before or within 1 year of the onset of motor symptoms in Parkinson’s disease. Depressive symptoms in patients with Parkinson’s disease must be taken seriously, because depressive symptoms very much affect the effectiveness of Parkinson’s disease treatment. The following is a compilation of some psychological guidance on depression, and I hope that patients and their families can read it carefully, so that it can be helpful to everyone.