High creatine kinase due to physiological factors can be cured by itself, while high creatine kinase due to pathological factors such as myocardial infarction and myocarditis cannot be cured by itself and requires prompt medical attention. Creatine kinase CK is mainly found in the cytoplasm and mitochondria of skeletal muscle, cardiac muscle, smooth muscle and other tissues, and will increase when these tissues are fatigued or pathologically injured. Normal adult blood creatine kinase CK levels are approximately 50-310 U/L in men and 40-200 U/L in women. Physiological factors, such as after strenuous and prolonged exercise, can lead to elevated creatine kinase CK, but this is mostly due to tissue stimulation, and usually recovers on its own after rest. However, if creatine kinase CK is elevated due to pathologic factors such as acute myocardial infarction, myocarditis, etc., it cannot recover on its own and must receive timely intervention. Specific therapeutic measures vary widely depending on the primary disease. It is recommended to go to the hospital in time to see if there is any disease when creatine kinase CK is elevated, especially after non-strenuous activities or when it is accompanied by obvious discomfort, so as not to miss the opportunity of treatment.