There is no quick pain relief for toe gout, which is often treated by applying non-steroidal anti-inflammatory drugs (NSAIDs), hormonal drugs, colchicine and other medications for pain relief. Gout is a disease triggered by high blood uric acid levels causing uric acid crystals to be deposited in the joints. Clinical manifestations often include severe pain in the joints of the metatarsals, toes and ankles, often occurring at night and accompanied by redness, swelling of the joint skin and elevated skin temperature. In the acute attack of toe gout, non-steroidal anti-inflammatory drugs such as indomethacin and diclofenac sodium can be used for pain relief, and colchicine can also be used for pain relief. When colchicine and NSAIDs are not effective for pain relief, glucocorticosteroids such as prednisone acetate can be used for a short period of time for analgesia. When the symptoms of gout appear in the toe, you should go to the hospital in time, under the guidance of the doctor, avoid self-medication, so as not to delay the condition or adverse reactions.