For the occasional itchy urethra, it is mainly considered to be caused by unhygienic private parts. If the symptoms do not disappear or even worsen when the private parts are kept clean, it is considered to be caused by diseases, and it is recommended to go to the hospital in time to find out the cause and carry out targeted treatment. The actual itchy urethra can be considered from the aspect of gender because of the different physiological structure of men and women, women mainly consider urethritis and vaginitis, men mainly consider prostatitis and foreskin glansitis, etc. The actual UTI is an acute and chronic inflammation that can be transmitted through sexual intercourse, often manifesting as itchy urethra, urinary urgency, painful urination and the appearance of urethral secretions. The clinical treatment of urethritis is usually carried out together with the spouse to avoid reinfection, mainly using antibacterial drugs, such as penicillin, etc.; 2. Vaginitis: because the female vagina is closer to the urethra, it is easy to spread to the urethra, and in addition to itching of the urethra, it is accompanied by symptoms such as hematuria, urinary frequency, urinary urgency, urinary pain, etc. The treatment of vaginitis is mainly through oral metronidazole antibiotic drugs, as well as clotrimazole and other vaginal The main treatment for vaginitis is oral antibiotics such as metronidazole and vaginal antifungal drugs such as clotrimazole. The same antibiotics are preferred for treatment, such as gentamicin, triclopirox and metronidazole, and can be combined with external application of miconazole ointment and other drugs. When there is a long-term itchy urethra and often accompanied by other symptoms, it is recommended to follow the doctor’s advice to actively treat, in addition to maintain private hygiene in general, especially do not have sex during women’s menstruation, so as not to increase the chance of infection.